Filmography
| Year | Title | Role |
| 2026 | Minions & Monsters (2026) | Voice |
| 2026 | The Dog Stars (2026) | Actor |
| 2025 | Another Simple Favor (2025) | Aunt Linda McLanden |
| 2025 | The Roses (2025) | Amy |
| 2025 | Everything's Going to Be Great (2025) | Macy Smart |
| 2023 | The Creator (2023) | Colonel Howell |
| 2022 | Still Working 9 to 5 (2022) | Self |
| 2022 | To Leslie (2022) | Nancy |
| 2021 | Breaking News in Yuba County | Sue Buttons |
| 2019 | Ma (2019) | Doctor Brooks |
| 2019 | The Addams Family (2019) | Margaux Needler |
| 2019 | Bombshell (2019) | Susan Estrich |
| 2019 | Troop Zero | Miss Massey |
| 2017 | I, Tonya | LaVona Golden |
| 2017 | A Happening of Monumental Proportions | Principal Nichols |
| 2016 | Miss Peregrine's Home for Peculiar Children | Dr. Golan |
| 2016 | The Girl on the Train | Detective Riley |
| 2016 | Tallulah | Actor |
| 2015 | Minions (2015) | Madge Nelson |
| 2015 | The DUFF | Dottie |
| 2015 | Spy (2015) | Elaine Crocker |
| 2014 | Mr. Peabody & Sherman | Miss Grunion |
| 2014 | Tammy | Deb |
| 2014 | Bad Words | Dr. Bernice Deagan |
| 2014 | The Rewrite | Mary Weldon |
| 2013 | Trust Me | Meg |
| 2013 | Touchy Feely | Bronwyn |
| 2013 | The Way, Way Back | Betty |
| 2013 | Brightest Star | The Astronomer |
| 2013 | Days and Nights | Elizabeth |
| 2012 | A Thousand Words | Samantha Davis |
| 2012 | Struck by Lightning | Sheryl Phillips |
| 2012 | Liberal Arts | Judith |
| 2011 | Margaret (2011) | Monica |
| 2011 | The Help | Charlotte Phelan |
| 2011 | The Oranges | Cathy |
| 2009 | Away We Go | Lily |
| 2009 | Life During Wartime | Trish Maplewood |
| 2007 | Hairspray (2007) | Prudy Pingleton |
| 2007 | Juno | Bren |
| 2006 | Over the Hedge | Gladys |
| 2005 | The Chumscrubber | Mrs. Stiffle |
| 2005 | Strangers with Candy | Alice |
| 2005 | Our Very Own | Joan Whitfield |
| 2004 | Winter Solstice | Molly Ripkin |
| 2003 | Finding Nemo | Peach |
| 2003 | How to Deal | Lydia Martin |
| 2002 | The Hours | Sally Lester |
| 2000 | Nurse Betty | Lyla Branch |
| 1999 | American Beauty (1999) | Barbara Fitts |
| 1999 | Drop Dead Gorgeous | Loretta |
| 1999 | 10 Things I Hate About You | Ms. Perky |
| 1998 | The Object Of My Affection | Constance Miller |
| 1998 | David and Lisa (1998) | Alix |
| 1998 | Primary Colors | Miss Walsh |
| 1998 | The Impostors | Maxine |
| 1997 | Private Parts | Dee Dee |
| 1996 | Big Night | Ann |
