Filmography
| Year | Title | Role |
| 2025 | Spinal Tap II: The End Continues (2025) | Marty DiBergi |
| 2024 | God & Country (2024) | Producer |
| 2022 | Family Squares (2022) | Narrator |
| 2017 | Shock and Awe (2018) | John Walcott |
| 2016 | Norman Lear: Just Another Version of You | Self |
| 2016 | LBJ | Director, Producer |
| 2016 | The Last Laugh (2017) | Self |
| 2015 | Being Charlie | Director, Producer |
| 2014 | And So It Goes | Artie |
| 2013 | The Wolf of Wall Street (2013) | Max Belfort |
| 2012 | The Magic of Belle Isle | Director, Producer |
| 2010 | Flipped | Director, Producer, Screenwriter |
| 2007 | The Bucket List | Director |
| 2007 | Certifiably Jonathan | Self |
| 2006 | Everyone's Hero | Screwie |
| 2005 | Rumor Has It | Director |
| 2003 | Alex & Emma | Wirschafter |
| 2003 | Dickie Roberts: Former Child Star | Self |
| 1999 | Muse | Self |
| 1999 | Forever Hollywood (1999) | Self |
| 1999 | EDtv | Mr. Whitaker |
| 1998 | Primary Colors | Izzy Rosenblatt |
| 1996 | Ghosts of Mississippi | Director, Producer |
| 1996 | The First Wives Club | Dr. Morris Packman |
| 1996 | Mad Dog Time / Reservoir Dogs | Albert the Chauffeur |
| 1995 | The American President | Director, Producer |
| 1994 | Bullets Over Broadway | Sheldon Flender |
| 1994 | Mixed Nuts | Dr. Kinsky |
| 1993 | Sleepless in Seattle (1993) | Jay |
| 1992 | A Few Good Men | Director, Producer |
| 1990 | Misery | Director, Producer |
| 1990 | Postcards From the Edge | Joe Pierce |
| 1990 | Spirit of '76 | Dr. Cash |
| 1989 | When Harry Met Sally... | Director, Producer |
| 1987 | The Princess Bride | Director |
| 1987 | Throw Momma From the Train | Joel |
| 1986 | Stand by Me (1986) | Director |
| 1985 | The Sure Thing | Director |
| 1984 | This Is Spinal Tap 41st Anniversary | Marty DiBergi |
| 1977 | Fire Sale | Russel Fikus |
| 1975 | How Come Nobody's on Our Side? | Miguelito |
| 1970 | Where's Poppa? | Roger, the Defendant |
| 1967 | Enter Laughing | Clark Baxter |
