Filmography
| Year | Title | Role |
| 2025 | Smurfs (2025) | Asmodius |
| 2025 | Tow (2026) | Actor |
| 2022 | The Quest for Sleep | Narrator |
| 2022 | Spirited (2022) | Kimberly |
| 2021 | Right to Try | Producer |
| 2021 | Encounter (2021) | Hattie |
| 2020 | Onward | Manticore |
| 2020 | Dolittle (2020) | Dab-Dab |
| 2019 | Ma (2019) | Sue Ann |
| 2019 | Luce | Harriet Carter |
| 2018 | A Kid Like Jake | Judy |
| 2018 | Green Book | Executive Producer |
| 2018 | Instant Family (2018) | Karen |
| 2017 | Gifted | Roberta |
| 2017 | The Shack | Papa |
| 2017 | The Shape of Water (2017) | Zelda Fuller |
| 2017 | Small Town Crime | Kelly Banks |
| 2016 | Zootopia (2016) | Mrs. Otterton |
| 2016 | The Divergent Series: Allegiant | Johanna |
| 2016 | The Free World | Linda Workman |
| 2016 | Hidden Figures | Dorothy Vaughan |
| 2016 | Bad Santa 2 | Opal |
| 2016 | The Great Gilly Hopkins | Ms. Harris |
| 2016 | Car Dogs | Mrs. Barrett |
| 2015 | B.O.O.: Bureau of Otherworldly Operations | Voice |
| 2015 | The Divergent Series: Insurgent | Johanna |
| 2015 | Fathers and Daughters | Dr. Corman |
| 2014 | Black or White | Rowena Jeffers |
| 2014 | Get On Up (2014) | Aunt Honey |
| 2013 | Percy Jackson: Sea of Monsters | Martha |
| 2013 | Fruitvale Station (2013) | Wanda |
| 2013 | Snowpiercer | Tanya |
| 2013 | Call Me Crazy | Dr. Nance |
| 2012 | Smashed | Jenny |
| 2012 | Blues for Willadean | LaSonia Robinson |
| 2012 | Lost on Purpose | Nurse Keller |
| 2011 | The Help | Minny |
| 2011 | Flypaper | Madge Wiggins |
| 2010 | Dinner for Schmucks | Madame Nora |
| 2009 | Jesus People | Angel Angelique |
| 2009 | Herpes Boy | Rochelle |
| 2008 | Pretty Ugly People | Mary |
| 2007 | The Nines | Streetwalker |
| 2004 | Breakin' All the Rules | Stylist |
| 2000 | Big Momma's House (2000) | Twila |
| 1999 | Blue Streak | Shawna |
