Filmography
| Year | Title | Role |
| 2024 | Wolfs (2024) | Margaret's Man |
| 2023 | The Boys in the Boat (2023) | Director, Producer |
| 2022 | Ticket to Paradise (2022) | David |
| 2021 | The Tender Bar (2021) | Director, Producer |
| 2020 | The Midnight Sky (2020) | Augustine |
| 2018 | Always at The Carlyle | Self |
| 2017 | Suburbicon | Director, Producer, Screenwriter |
| 2016 | Money Monster | Lee Gates |
| 2016 | Hail, Caesar! | Baird Whitlock |
| 2016 | Norman Lear: Just Another Version of You | Self |
| 2015 | Tomorrowland | Frank Walker |
| 2015 | Our Brand Is Crisis (2015) | Producer |
| 2014 | The Monuments Men | Frank Stokes |
| 2013 | Gravity | Matt Kowalsky |
| 2013 | August: Osage County | Producer |
| 2013 | JFK: One PM Central Standard Time | Actor |
| 2012 | Argo | Producer |
| 2012 | Radioman | Actor |
| 2011 | The Descendants | Matt King |
| 2011 | His Way | Self |
| 2011 | The Ides of March | Gov. Mike Morris |
| 2010 | The American | Jack/Edward |
| 2009 | Fantastic Mr. Fox | Mr. Fox |
| 2009 | The Informant! | Executive Producer |
| 2009 | The Men Who Stare at Goats | Lyn Cassady |
| 2009 | Up in the Air | Ryan Bingham |
| 2009 | Playground | Executive Producer |
| 2008 | Leatherheads | Dodge Connolly |
| 2008 | Burn After Reading | Harry Pfarrer |
| 2008 | Annie Leibovitz: Life Through a Lens | Actor |
| 2007 | Ocean's Thirteen | Danny Ocean |
| 2007 | Wind Chill | Executive Producer |
| 2007 | Michael Clayton | Michael Clayton |
| 2007 | Sand and Sorrow | Executive Producer, Narrator |
| 2007 | Darfur Now | Self |
| 2006 | A Scanner Darkly | Executive Producer |
| 2006 | The Good German | Jake Geismar |
| 2006 | The Half Life Of Timofey Berezin | Executive Producer |
| 2005 | Syriana | Robert Baer |
| 2005 | The Jacket | Executive Producer, Producer |
| 2005 | Rumor Has It | Producer |
| 2005 | Good Night, and Good Luck | Fred Friendly |
| 2004 | Ocean's Twelve | Danny Ocean |
| 2004 | Criminal (2004) | Producer |
| 2003 | Spy Kids 3-D: Game Over | Devlin |
| 2003 | Intolerable Cruelty | Miles Massey |
| 2002 | Welcome to Collinwood | Jerzy |
| 2002 | Confessions of a Dangerous Mind | CIA Agent Jim Byrd |
| 2002 | Solaris | Chris Kelvin |
| 2002 | Far From Heaven | Executive Producer |
| 2001 | Rock Star | Executive Producer |
| 2001 | Ocean's Eleven (1960) | Danny Ocean |
| 2000 | The Perfect Storm | Captain Billy Tyne |
| 2000 | O Brother, Where Art Thou? | Everett Ulysses McGill |
| 1999 | Three Kings | Maj. Archie Gates |
| 1999 | South Park: Bigger Longer & Uncut Movie Party | Dr. Gouache/Dr. Doctor |
| 1998 | The Thin Red Line | Capt. Bosche |
| 1998 | Out of Sight (1998) | Jack Foley |
| 1997 | Batman & Robin | Bruce Wayne/Batman |
| 1996 | From Dusk Till Dawn | Seth Gecko |
| 1996 | One Fine Day | Jack Taylor |
| 1988 | Return of the Killer Tomatoes | Matt Stevens |
| 1983 | Grizzly II: Revenge | Ron |
