Filmography
| Year | Title | Role |
| 1966 | Walk Don't Run: The Story of the Ventures | Sir William Rutland |
| 1964 | Father Goose | Walter Christopher Eckland |
| 1963 | Charade | Peter Joshua |
| 1962 | That Touch of Mink | Philip Shayne |
| 1960 | The Grass Is Greener | Victor Rhyall |
| 1959 | North by Northwest (1959) | Roger O. Thornhill/George Kaplan |
| 1959 | Operation Petticoat | Lt. Cmdr. Matt T. Sherman |
| 1958 | Houseboat | Tom Winters |
| 1957 | An Affair to Remember | Nickie Ferrante |
| 1957 | The Pride And The Passion | Anthony |
| 1957 | Kiss Them for Me | Commander Andy Crewson |
| 1955 | To Catch a Thief | John Robie |
| 1953 | Dream Wife | Clemson Reade |
| 1952 | Room for One More | George Rose |
| 1952 | Monkey Business | Dr. Barnaby Fulton |
| 1950 | Crisis (1950) | Dr. Eugene Norland Ferguson |
| 1949 | I Was a Male War Bride | Capt. Henri Rochard |
| 1948 | Every Girl Should Be Married | Dr. Madison W. Brown |
| 1948 | Mr. Blandings Builds His Dream House | Jim Blandings |
| 1947 | The Bishop's Wife | Dudley |
| 1947 | The Bachelor and the Bobby-Soxer | Dick |
| 1946 | Notorious (1946) | T.R. Devlin |
| 1944 | Arsenic and Old Lace (1969) | Mortimer Brewster |
| 1944 | None but the Lonely Heart | Ernie Mott |
| 1944 | Once Upon a Time in Corea | Jerry Flynn |
| 1943 | Destination Tokyo | Capt. Cassidy |
| 1943 | Mr. Lucky | Joe Adams/Joe Bascopolous |
| 1942 | Once Upon a Honeymoon | Patrick "Pat" O'Toole |
| 1942 | The Talk of the Town | Leopold Dilg/Joseph |
| 1941 | Penny Serenade | Roger Adams |
| 1941 | Suspicion | Johnnie Aysgarth |
| 1940 | His Girl Friday | Walter Burns |
| 1940 | The Philadelphia Story (1940) | C. K. Dexter Haven |
| 1940 | My Favorite Wife | Nick |
| 1940 | The Howards Of Virginia | Matt Howard |
| 1939 | Gunga Din | Sgt. Archibald Cutter |
| 1939 | In Name Only | Alec Walker |
| 1939 | Only Angels Have Wings | Geoff Carter |
| 1938 | Bringing Up Baby | Dr. David Huxley |
| 1938 | Holiday (1938) | Johnny Case |
| 1937 | When You're in Love | Jimmy Hudson |
| 1937 | The Awful Truth | Jerry Warriner |
| 1937 | Topper | George Kerby |
| 1936 | Big Brown Eyes | Det. Sgt. Danny Barr |
| 1936 | Wedding Present | Charlie Mason |
| 1936 | The Amazing Adventure | Ernest Bliss |
| 1935 | Sylvia Scarlett | Jimmy "Monk" Monkley |
| 1934 | Born to Be Bad | Malcolm Trevor |
| 1934 | Thirty Day Princess | Porter Madison III |
| 1934 | Kiss and Make Up | Dr. Maurice Lamar |
| 1934 | Ladies Should Listen | Julian De Lussac |
| 1933 | I'm No Angel | Jack Clayton |
| 1933 | She Done Him Wrong | Capt. Cummings |
| 1933 | Woman Accused | Jeffrey Baxter |
| 1933 | Gambling Ship | Ace Corbin |
| 1932 | Blonde Venus | Nick Townsend |
| 1932 | Sinners in the Sun | Ridgeway |
| 1932 | Hot Saturday | Romer Sheffield |
| 1932 | This Is the Night (1932) | Stephen |
| 1932 | Opera: Madame Butterfly | Lieutenant B.F. Pinkerton |
| 1932 | The Devil and the Deep | Lt. Jaeckel |
