- Robert De Niro
- Frank Sheeran, Producer
- Al Pacino
- Jimmy Hoffa
- Joe Pesci
- Russell Bufalino
- Anna Paquin
- Peggy Sheeran
- Harvey Keitel
- Angelo Bruno
- Stephen Graham
- Anthony Provenzano
- Bobby Cannavale
- Felix 'Skinny Razor' DiTullio
- Aleksa Palladino
- Mary Sheeran
- Domenick Lombardozzi
- Anthony Salerno
- Kathrine Narducci
- Carrie Bufalino
- Ray Romano
- Bill Bufalino
- Sebastian Maniscalco
- Joseph 'Crazy Joe' Gallo
- Jesse Plemons
- Chuckie O'Brien
- Jake Hoffman
- Allen Dorfman
- Jeremy Luke
- Thomas Andretta
- Stephanie Kurtzuba
- Irene Sheeran
- India Ennenga
- Dolores Sheeran
- J.C. MacKenzie
- Jimmy Neal
- Gary Basaraba
- Frank 'Fitz' Fitzsimmons
- Jack Huston
- Robert F. Kennedy
- Larry Romano
- Phil Testa
- Barry Primus
- Ewing King
- Martin Scorsese
- Director, Producer
- Steven Zaillian
- Screenwriter
- Robert De Niro
- Frank Sheeran, Producer
- Jane Rosenthal
- Producer
- Gastón Pavlovich
- Producer
- Randall Emmett
- Producer
- Emma Tillinger Koskoff
- Producer
- Gerald Chamales
- Producer
- Irwin Winkler
- Producer
- Troy Allen
- Producer
- Richard Baratta
- Executive Producer
- Niels Juul
- Executive Producer
- Jai Stefan
- Executive Producer
- Chad A. Verdi
- Executive Producer
- Berry Welsh
- Executive Producer
- Tyler Zacharia
- Executive Producer
- Rick Yorn
- Executive Producer
- Nicholas Pileggi
- Executive Producer
- Rodrigo Prieto
- Cinematographer
- Thelma Schoonmaker
- Film Editing
- Robbie Robertson
- Original Music
- Bob Shaw
- Production Design
- Christopher Peterson
- Costume Design
- Sandy Powell
- Costume Design
- Ellen Lewis
- Casting
