- George C. Scott
- Dr. Herbert Bock
- Diana Rigg
- Miss Barbara Drummond
- Barnard Hughes
- Edmund Drummond
- Richard Dysart
- Dr. Welbeck
- Andrew Duncan
- William Mead
- Nancy Marchand
- Mrs. Christie
- Stephen Elliott
- Dr. John Sundstrom
- Donald Harron
- Dr. Milton Mead
- Roberts Blossom
- Guernsey
- Robert Walden
- Dr. Brubaker
- Frances Sternhagen
- Mrs. Cushing
- Nancy MacKay
- Sheilah (uncredited)
- Lenny Baker
- Dr. Howard Schaefer
- David Hooks
- Dr. Einhorn
- Arthur Junaluska
- Mr. Blacktree
- Rehn Scofield
- Dr. Spezio
- Kate Harrington
- Nurse Dunne
- Jordan Charney
- Hitchcock
- Tresa Hughes
- Mrs. Donovan (uncredited)
- Lorrie Davis
- Nurse Divine (uncredited)
- Norman Berns
- Dr. Biegelman (uncredited)
- Cynthia Belgrave
- Nurse Reardon (uncredited)
- Julie Garfield
- Nurse Perez (uncredited)
- Janet Sarno
- Nurse Rivers (uncredited)
- Angie Ortega
- Nurse Teresa Campanella (uncredited)
- Charles Bershatsky
- Medical Student Boswell (uncredited)
- Paul Mace
- Intern Ambler (uncredited)
- Lou Polan
- Dr. Lagerman (uncredited)
- Richard Goode
- Dr. Sutcliffe (uncredited)
- Arthur Hiller
- Director
- Paddy Chayefsky
- Writer
- Howard Gottfried
- Producer
- Jack Grossberg
- Associate Producer
- Morris Surdin
- Original Music
- Victor J. Kemper
- Cinematographer
- Eric Albertson
- Film Editing
- Gene Rudolf
- Production Design
- Herbert F. Mulligan
- Set Decoration
- Frank L. Thompson
- Costume Design
- Vincent Callaghan
- Makeup Artist
- Larry Y. Albucher
- Second Assistant Director
- Peter R. Scoppa
- First Assistant Director
