- Oakes Fegley
- Young Theo Decker
- Ansel Elgort
- Adult Theo Decker
- Nicole Kidman
- Mrs. Barbour
- Jeffrey Wright
- Hobie
- Luke Wilson
- Larry
- Sarah Paulson
- Xandra
- Willa Fitzgerald
- Adult Kitsey Barbour
- Aneurin Barnard
- Adult Boris
- Finn Wolfhard
- Young Boris
- Ashleigh Cummings
- Adult Pippa
- Aimee Laurence
- Young Pippa
- Robert Joy
- Welty
- Boyd Gaines
- Mr. Barbour
- Carly Connors
- Young Kitsey Barbour
- Luke Kleintank
- Adult Platt Barbour
- Hailey Wist
- Theo's Mother
- Ryan Foust
- Young Andy Barbour
- Jack DiFalco
- Young Platt Barbour
- Austin Weyant
- Adult Toddy Barbour
- Collin Shea Schirrmacher
- Young Toddy Barbour
- Denis O'Hare
- Lucius Reeve
- John Crowley
- Director
- Peter Straughan
- Screenwriter
- Donna Tartt
- Screenwriter
- Mari-Jo Winkler
- Executive Producer
- Kevin McCormick
- Executive Producer
- Sue Kroll
- Executive Producer
- Courtenay Valenti
- Executive Producer
- Nina Jacobson
- Producer
- Brad Simpson
- Producer
- Roger Deakins
- Cinematographer
- Kelley Dixon
- Film Editing
- Trevor Gureckis
- Original Music
- K.K. Barrett
- Production Design
- Deborah Jensen
- Art Director
- Rena DeAngelo
- Set Decoration
- Kasia Walicka Maimone
- Costume Design
- Ellen Chenoweth
- Casting
