- Sylvester Stallone
- John Rambo, Screenwriter
- Paz Vega
- Carmen
- Sergio Peris-Mencheta
- Hugo Martínez
- Adriana Barraza
- Maria Beltran
- Yvette Monreal
- Gabriela
- Genie Kim
- Bar Patron
- Joaquín Cosio
- Don Manuel
- Pascacio López
- El Flaco
- Óscar Jaenada
- Victor Martinez
- Alexander Dimitrov
- Heli Pilot
- Aaron Cohen
- State Police Captain
- Nick Wittman
- Male Hiker
- Jessica Madsen
- Becky
- Louis Mandylor
- Sheriff
- Owen Davis
- Rescue Worker
- Marco De La O Ríos
- Manuel
- Adrian Grunberg
- Director
- Matthew Cirulnick
- Screenwriter
- Sylvester Stallone
- John Rambo, Screenwriter
- Avi Lerner
- Producer
- Kevin King Templeton
- Producer
- Yariv Lerner
- Producer
- Les Weldon
- Producer
- Liu Rong
- Executive Producer
- Jeffrey Greenstein
- Executive Producer
- Jonathan Yunger
- Executive Producer
- Christa Campbell
- Executive Producer
- Lati Grobman
- Executive Producer
- Ariel Vromen
- Executive Producer
- Brendan Galvin
- Cinematographer
- Todd E. Miller
- Film Editing
- Carsten Kurpanek
- Film Editing
- Brian Tyler
- Original Music
- Franco-Giacomo Carbone
- Production Design
- Kes Bonnet
- Supervising Art Direction
- Emil Gigov
- Art Director
- Eduardo Hidalgo
- Art Director
- David Temprano
- Art Director
- Valentina Mladenova
- Set Decoration
- Nieves Monterde
- Set Decoration
- Cristina Sopeña
- Costume Design
- Carla Hool
- Casting
