Filmography
| Year | Title | Role |
| 2025 | Nobody 2 (2025) | Lendina |
| 2023 | What About Love (2022) | Linda Tarlton |
| 2019 | Rolling Thunder Revue: A Bob Dylan Story by Martin Scorsese | The Beauty Queen |
| 2019 | The Laundromat (2019) | Hannah |
| 2017 | The Disaster Artist (2017) | Iris Burton |
| 2017 | Romantic Road | Executive Producer |
| 2017 | All I Wish | Senna Berges |
| 2017 | Into the Night: Portraits of Life and Death | Narrator |
| 2016 | Harry Benson: Shoot First | Self |
| 2016 | Mothers and Daughters (2016) | Nina |
| 2015 | Life on the Line | Duncan's Mother |
| 2014 | Dior and I | Self |
| 2014 | My Name Is Water | Producer |
| 2014 | A Golden Boy | Ludovica Stern |
| 2013 | Lovelace | Dorothy Boreman |
| 2013 | Femme (2013) | Self |
| 2013 | Fading Gigolo | Dr. Parker |
| 2012 | Border Run | Sofie |
| 2008 | The Year of Getting to Know Us | Jane Rocket |
| 2008 | $5 a Day | Dolores Jones |
| 2006 | Bobby (2006) | Miriam |
| 2006 | Alpha Dog | Olivia Mazursky |
| 2006 | Basic Instinct 2 | Catherine Trammell |
| 2006 | Wassup Rockers | Executive Producer |
| 2005 | Broken Flowers | Laura |
| 2004 | Catwoman | Laurel Hedare |
| 2004 | A Different Loyalty | Sally Tyler / Cauffield |
| 2004 | Jiminy Glick in Lalawood | Self |
| 2003 | Cold Creek Manor | Leah Tilson |
| 2000 | If These Walls Could Talk 2 | Fran |
| 1999 | Muse | Sarah Little |
| 1999 | Forever Hollywood (1999) | Narrator |
| 1998 | Antz | Princess Bala |
| 1998 | The Mighty | Gwen Dillon |
| 1998 | Sphere | Dr. Beth Halperin |
| 1996 | Diabolique (1996) | Nicole Horner |
| 1995 | The Quick And The Dead | The Lady/Ellen |
| 1995 | Casino (1995) | Ginger McKenna/Rothstein |
| 1993 | Sliver | Carly Norris |
| 1992 | Basic Instinct | Catherine Tramell |
| 1991 | He Said, She Said | Linda |
| 1990 | Total Recall (1990) | Lori |
| 1988 | Above the Law | Sara Toscani |
| 1988 | Action Jackson (1988) | Patrice Dellaplane |
| 1987 | Police Academy 4: Citizens on Patrol | Claire Mattson |
| 1984 | Irreconcilable Differences | Blake Chandler |
| 1981 | Deadly Blessing | Lana Marcus |
