Filmography
| Year | Title | Role |
| 2018 | Incredibles 2 | Helen Parr/Elastigirl |
| 2017 | Song to Song | Miranda |
| 2017 | The Big Sick | Beth |
| 2017 | Breakable You | Eleanor Weller |
| 2016 | Batman v Superman: Dawn of Justice | Senator Finch |
| 2016 | Strange Weather | Darcy Baylor |
| 2014 | Manglehorn | Dawn |
| 2007 | Rock That Uke | Actor |
| 2005 | The Big White | Margaret Barnell |
| 2005 | Nine Lives (2005) | Sonia |
| 2004 | The Incredibles (2004) | Helen Parr/Elastigirl |
| 2004 | Little Black Book (2004) | Barb |
| 2003 | Thirteen | Melanie |
| 2003 | Levity | Adele Easley |
| 2002 | Moonlight Mile | Asst. D.A. Mona Camp |
| 2001 | Festival in Cannes | Self |
| 2001 | When Billie Beat Bobby | Billie Jean King |
| 2000 | Timecode (2000) | Executive |
| 2000 | O Brother, Where Art Thou? | Penny |
| 2000 | Things You Can Tell Just by Looking at Her | Rebecca Waynon |
| 1999 | Jesus' Son | Mira |
| 1998 | Living Out Loud | Judith Moore |
| 1997 | A Life Less Ordinary | O'Reilly |
| 1996 | Crash (1996) | Dr. Helen Remington |
| 1995 | Home for the Holidays | Claudia Larson |
| 1993 | The Piano | Ada McGrath |
| 1993 | The Positively True Adventures of the Alleged Texas Cheerleader-Murdering Mom | Wanda Holloway |
| 1991 | Once Around | Renata Bella |
| 1989 | Always | Dorinda Durston |
| 1989 | Miss Firecracker | Carnelle Scott |
| 1989 | Roe vs. Wade (1989) | Ellen Russell/Jane Doe |
| 1988 | End of the Line | Charlotte |
| 1987 | Raising Arizona | Edwina "Ed" McDonnough |
| 1987 | Broadcast News | Jane Craig |
| 1987 | A Gathering of Old Men | Candy Marshall |
| 1984 | Swing Shift | Actor |
