Filmography
| Year | Title | Role |
| 2026 | Zero A.D. (2026) | Actor |
| 2025 | Holland (2025) | Dave Delgado |
| 2024 | Another End (2025) | Sal |
| 2023 | The Mother (2023) | Hector |
| 2023 | Cassandro (2023) | Saúl Armendáriz |
| 2021 | Old (2021) | Guy |
| 2019 | Chicuarotes | Director |
| 2019 | Ema (2021) | Gastón |
| 2018 | Museo | Juan Nuñez |
| 2017 | Coco (2017) | Héctor |
| 2017 | Zama | Executive Producer |
| 2016 | Salt and Fire | Dr. Fabio Cavani |
| 2016 | Neruda | Óscar Peluchonneau |
| 2016 | Eva Doesn't Sleep | Massera |
| 2016 | You're Killing Me Susana | Eligio |
| 2016 | Madly | Director, Screenwriter |
| 2015 | The Chosen Ones | Executive Producer |
| 2015 | The Empty Classroom | Producer, Voice |
| 2015 | Desierto | Moises |
| 2015 | Zoom (2016) | Edward |
| 2014 | Cesar Chavez | Executive Producer |
| 2014 | Rosewater | Maziar Bahari |
| 2014 | Ardor | Kai |
| 2013 | Who is Dayani Cristal? | Actor, Producer |
| 2013 | Paradise (2013) | Executive Producer |
| 2012 | Casa De Mi Padre | Onza |
| 2012 | No (2013) | René Saavedra |
| 2011 | A Little Bit of Heaven | Julian Goldstein |
| 2011 | The Loneliest Planet | Alex |
| 2011 | EL LENGUAJE DE LOS MACHETES | Executive Producer |
| 2010 | Letters to Juliet | Victor |
| 2010 | Abel | Executive Producer |
| 2010 | Even the Rain (Tambien La Lluvia) | Sebastián |
| 2009 | The Limits of Control | Mexican |
| 2009 | Sin Nombre | Executive Producer |
| 2009 | Mammoth | Leo |
| 2008 | Blindness | Bartender/King of Ward Three |
| 2008 | 8 | Director, Writer |
| 2008 | I'm Going to Explode | Executive Producer |
| 2008 | Rudo y Cursi | Tato |
| 2007 | Deficit | Cristobal |
| 2007 | El pasado | Rímini |
| 2007 | Cochochi | Executive Producer |
| 2006 | The Science of Sleep | Stéphane Miroux |
| 2006 | Drama/Mex | Executive Producer |
| 2004 | Bad Education | Ángel / Juan / Zahara |
| 2004 | The Motorcycle Diaries | Ernesto 'Che' Guevara de la Serna |
| 2003 | Dot the I | Kit |
| 2002 | El Crimen del Padre Amaro | Padre Amaro |
| 2001 | Vidas Privadas | Gustavo "Gana" Bertolini |
| 2001 | Bendito Infierno | Davenport |
| 2001 | And Your Mother Too | Julio Zapata |
| 2000 | Amores perros | Octavio |
| 2000 | Fidel | Actor |
