In 2006, they raced into our hearts with Talladega Nights: The Ballad of Ricky Bobby.
In 2008, they became part of our loveable dysfunctional family with Step Brothers.
Now, on December 21, Will Ferrell and John C. Reilly will once again reteam on the big screen to play the world’s greatest consulting detective and his loyal biographer: Holmes and Watson.
Fandango exclusively presents the very first trailer for Holmes & Watson below. Check it out.
For more, peep these exclusive images from Holmes & Watson below. The film, written and directed by Etan Cohen, arrives in theaters on December 21.