- Harrison Ford
- Captain Alexi Vostrikov, Executive Producer
- Liam Neeson
- Captain Mikhail Polenin
- Peter Sarsgaard
- Reactor Officer Vadim Radtchenko
- Joss Ackland
- Marshal Zelentsov
- John Shrapnel
- Admiral Bratyeev
- Donald Sumpter
- Dr. Savran
- Tim Woodward
- Partonov
- Steve Nicholson
- Demichev
- Ravil Isyanov
- Suslov
- Christian Camargo
- Pavel Loktev
- Sam Spruell
- Dmitri
- Peter Stebbings
- Kuryshev
- Roman Podhora
- Lapinsh
- Sam Redford
- Vasily
- Lex Shrapnel
- Kornilov
- Shaun Benson
- Leonid
- Kris Holden-Ried
- Anton
- Dmitry Chepovetsky
- Sergei
- Christopher Redman
- Kiklidze
- Tygh Runyan
- Maxim
- George Anton
- Konstantin
- James Francis Ginty
- Anatoly
- Peter Graham
- Lt. Danya Yashin
- Shawn Mathieson
- Stepan
- Jacob Pitts
- Grigori
- Christopher Routh
- Oleg
- Lubomir Mykytiuk
- Dr. Gavril
- Michael Gladis
- Yevgeny Borzenkov
- Natal'ya Vintilova
- Katya
- Steve Cumyn
- Arseni
- Austin Strugnell
- Yakov Rakitin
- Arsenty Sydelnykov
- Seymon 'Syoma' Dydik
- JJ Feild
- Andrei
- Peter Oldring
- Vanya
- Joshua Close
- Viktor
- Ingvar Eggert Sigurðsson
- Chief Engineer Gorelov
- Gerrit Vooren
- Voslensky
- Joey Purpura
- Georgi
- Lev Prygunov
- Ivan Vershinin
- Jeremy Akerman
- Fyodor Tsetkov
- Lee J. Campbell
- Judge
- Kathryn Bigelow
- Director, Producer
- Christopher Kyle
- Screenwriter
- Sigurjon Sighvatsson
- Producer
- Christine Whitaker
- Producer
- Edward S. Feldman
- Producer
- Harrison Ford
- Captain Alexi Vostrikov, Executive Producer
- Nigel Sinclair
- Executive Producer
- Moritz Borman
- Executive Producer
- Guy East
- Executive Producer
- Jeff Cronenweth
- Cinematographer
- Karl Juliusson
- Production Design
- Michael Novotny
- Production Design
- Walter Murch
- Film Editing
- Marit Allen
- Costume Design
- Klaus Badelt
- Original Music
- Mali Finn
- Casting
- Mary Selway
- Casting
- Ross Clydesdale
- Casting
