- Liam Hemsworth
- Jake Morrison
- Jeff Goldblum
- David Levinson
- Bill Pullman
- President Whitmore
- Maika Monroe
- Patricia Whitmore
- Jessie T. Usher
- Dylan Hiller
- Travis Tope
- Charlie Miller
- Judd Hirsch
- Julius Levinson
- Charlotte Gainsbourg
- Dr. Catherine Marceaux
- William Fichtner
- General Adams
- Angelababy
- Rain Lao
- Nicolas Wright
- Floyd Rosenberg, Screenwriter
- Deobia Oparei
- Dikembe Umbutu
- Joey King
- Sam
- John Storey
- Dr. Isaacs
- Brent Spiner
- Dr. Brakish Okun
- Sela Ward
- President Lanford
- Vivica A. Fox
- Jasmine Hiller
- Chin Han
- Commander Jiang
- Robert Loggia
- General Grey
- Roland Emmerich
- Director, Producer, Screenwriter
- Dean Devlin
- Producer, Screenwriter
- Nicolas Wright
- Floyd Rosenberg, Screenwriter
- James A. Woods
- Screenwriter
- James Vanderbilt
- Screenwriter
- Harald Kloser
- Original Music, Producer
- Ute Emmerich
- Executive Producer
- Larry J. Franco
- Executive Producer
- Carsten H.W. Lorenz
- Executive Producer
- Markus Förderer
- Cinematographer
- Adam Wolfe
- Film Editing
- Thomas Wanker
- Original Music
- Barry Chusid
- Production Design
- Patrick M. Sullivan Jr.
- Art Director
- Jay Hart
- Set Decoration
- Lisy Christl
- Costume Design
- John Papsidera
- Casting