- Kyle Chandler
- Dr. Mark Russell
- Vera Farmiga
- Dr. Emma Russell
- Millie Bobby Brown
- Madison Russell
- Ken Watanabe
- Dr. Ishiro Serizawa
- Zhang Ziyi
- Dr. Ilene Chen/Dr. Ling
- Bradley Whitford
- Dr. Rick Stanton
- Sally Hawkins
- Dr. Vivienne Graham
- Charles Dance
- Alan Jonah
- Thomas Middleditch
- Sam Coleman
- Aisha Hinds
- Colonel Diane Foster
- O'Shea Jackson Jr.
- Chief Warrant Officer Barnes
- David Strathairn
- Admiral William Stenz
- Anthony Ramos
- Staff Sergeant Martinez
- Elizabeth Ludlow
- First Lieutenant Griffin
- Jonathan Howard
- Asher Jonah
- CCH Pounder
- Senator Williams
- Joe Morton
- Dr. Houston Brooks
- Michael Dougherty
- Director, Screenwriter
- Zach Shields
- Executive Producer, Screenwriter
- Mary Parent
- Producer
- Alex Garcia
- Producer
- Thomas Tull
- Producer
- Jon Jashni
- Producer
- Brian Rogers
- Producer
- Barry H. Waldman
- Executive Producer
- Hiro Matsuoka
- Executive Producer
- Keiji Ôta
- Executive Producer
- Dan Lin
- Executive Producer
- Roy Lee
- Executive Producer
- Yoshimitsu Banno
- Executive Producer
- Kenji Okuhira
- Executive Producer
- Lawrence Sher
- Cinematographer
- Roger Barton
- Film Editing
- Richard Pearson
- Film Editing
- Bob Ducsay
- Film Editing
- Bear McCreary
- Original Music
- Scott Chambliss
- Production Design
- John Dexter
- Art Director
- Natasha Gerasimova
- Art Director
- Harry E. Otto
- Art Director
- David Scott
- Art Director
- Thomas Valentine
- Art Director
- David Scott
- Art Director
- Amanda Moss Serino
- Set Decoration
- Luisa Guala
- Set Decoration
- Louise Mingenbach
- Costume Design
- Sarah Halley Finn
- Casting
