- Marion Cotillard
- Dr. Leonora Orantes
- Matt Damon
- Mitch Emhoff
- Laurence Fishburne
- Dr. Ellis Cheever
- Jude Law
- Alan Krumwiede
- Gwyneth Paltrow
- Beth Emhoff
- Kate Winslet
- Dr. Erin Mears
- Jennifer Ehle
- Dr. Ally Hextall
- Bryan Cranston
- RADM Lyle Haggerty
- Sanaa Lathan
- Aubrey Cheever
- John Hawkes
- Roger
- Demetri Martin
- Dr. David Eisenberg
- Elliott Gould
- Dr. Ian Sussman
- Enrico Colantoni
- Dennis French
- Larry Clarke
- Dave
- Anna Jacoby-Heron
- Jory
- Steven Soderbergh
- Cinematographer, Director
- Scott Z. Burns
- Screenwriter
- Michael Shamberg
- Producer
- Stacey Sher
- Producer
- Gregory Jacobs
- Producer
- Jeff Skoll
- Executive Producer
- Michael Polaire
- Executive Producer
- Jonathan King
- Executive Producer
- Howard Cummings
- Production Design
- Stephen Mirrione
- Film Editing
- Louise Frogley
- Costume Design
- Cliff Martinez
- Original Music
- Carmen Cuba
- Casting
- David Lazan
- Supervising Art Direction
- Cindy Carr
- Set Decoration
