- Javier Bardem
- Reinaldo Arenas
- Olivier Martinez
- Lazaro Gomez Carilles
- Andrea Di Stefano
- Pepe Malas
- Johnny Depp
- Bon Bon/Lieutenant Victor
- Sean Penn
- Cuco Sanchez
- Michael Wincott
- Herberto Zorilla Ochoa
- Najwa Nimri
- Fina Correa
- Hector Babenco
- Virgilio Pinera
- Olatz Lopez Garmendia
- Reinaldo's Mother, Executive Producer
- Vito Maria Schnabel
- Teenage Reinaldo
- Jerzy Skolimowski
- Professor
- Julian Schnabel
- Director, Executive Producer, Writer
- Reynaldo Arenas
- Writer
- Lázaro Gómez Carriles
- Writer
- Cunningham O'Keefe
- Writer
- Jon Kilik
- Producer
- Olatz Lopez Garmendia
- Reinaldo's Mother, Executive Producer
- Matthias Ehrenberg
- Associate Producer
- Xavier Grobet
- Cinematographer
- Guillermo Rosas
- Cinematographer
- Michael Berenbaum
- Film Editing
- Carter Burwell
- Original Music
- Laurie Anderson
- Additional Music
- Lou Reed
- Additional Music
- Salvador Parra
- Production Design
- Antonio Muño-Hierro
- Art Director
- Laurie Friedman
- Set Decoration
- María Estela Fernández
- Costume Design
- Monica Nordhaus
- Casting
- Batan Silva
- Assistant Director
- Christian Wangler
- Sound
- Yvette Gurza
- Second Assistant Director
- Joaquin Silva
- Second Assistant Director
