- Amy Adams
- Bev
- Glenn Close
- Mawmaw
- Gabriel Basso
- J.D. Vance
- Freida Pinto
- Usha
- Sunny Mabrey
- Bonnie - Mamaw 30s
- Bo Hopkins
- Papaw
- Dylan Gage
- Kameron
- David Atkinson
- Ray
- Haley Bennett
- Lindsay
- Asztalos Gyula Owen
- Young J.D. Vance
- Jesse C. Boyd
- Matt
- Stephen Kunken
- Phillip Roseman
- Keong Sim
- Ken
- Morgan Gao
- Travis
- Ethan Suess
- Chris
- Jono Mitchell
- Kevin
- Bill Kelly
- Uncle Pet
- David Dwyer
- Uncle Arch
- Sarah Hudson
- Lori
- Ted Huckabee
- Jimmy (Bev's Brother)
- Nathan Hesse
- Bill (Nurse)
- Max Barrow
- Cousin Nate
- Brett Lorenzini
- Jim (Papaw, 30's)
- Tierney Smith
- Young Bev (6 years)
- Helen LeRoy
- Cheryl
- Kinsley Isla Dillon
- Emma
- Ryan Homchick
- Adult Frank McFee
- Joshua Stenvick
- Chip
- Bill Winkler
- Brooks Houghton
- Chase Anderson
- Brett
- Amy Parrish
- Pamela
- Ed Amatrudo
- Rich
- David de Vries
- Hiram Walcott
- Ron Howard
- Director, Producer
- Vanessa Taylor
- Screenwriter
- Brian Grazer
- Producer
- Karen Lunder
- Producer
- Julie Oh
- Executive Producer
- Kevin Halloran
- Executive Producer
- J.D. Vance
- Executive Producer
- William M. Connor
- Executive Producer
- Maryse Alberti
- Cinematographer
- James Wilcox
- Film Editing
- Dave Fleming
- Original Music
- Molly Hughes
- Production Design
- Shawn D. Bronson
- Art Director
- Laura Wallgren
- Set Decoration
- Virginia Johnson
- Costume Design
- Carmen Cuba
- Casting
