SpliceSynopsis

Poster premiere for "Splice."

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Celebrated genetic engineers Clive (Adrien Brody) and Elsa (Sarah Polley) conduct a clandestine experiment to create an animal/human hybrid that could revolutionize modern medicine -- if it doesn't destroy humanity first. On the heels of engineering an entirely new species of animal, Clive and Elsa become the toast of the scientific community. Their experiment begins to spiral out of control, however, when the superstar scientists introduce human DNA into the equation. When Dren is born, Clive and Elsa welcome her into the world as the next leap in human evolution. Now, the faster Dren evolves, the more her creators start to realize they may have made a catastrophic mistake. ~ Jason Buchanan, Rovi

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Exclusive Features

Splice 100 Days Fandango Review Is 'Splice' Creepy, Over-the-Top Sci-Fi Horror at it's Best? Day 32 of 100 Days of Movies finds Fandango editor Chuck Walton watching one shocking and disturbing movie. Watch our exclusive Sarah Polley Sundance 2010 interview! Sarah Polley talks about working with Adrien Brody and why she was drawn to this project! Exclusive director Vincenzo Natali Sundance 2010 interview!