Entertainment Weekly

By Lisa Schwarzbaum
A cheeky, great-looking, thoughtfully loopy creature feature about the lure and dangers of cutting-edge gene splicing.
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Wall Street Journal

By Joe Morgenstern
The film takes itself frivolously when that's appropriate--some of it is charmingly silly--and seriously when, as is often the case, all sorts of good surprises are unleashed.
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By Jeannette Catsoulis
The film's greatest accomplishment is its ability to change tone at least three times without losing the audience.
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Philadelphia Inquirer

By Carrie Rickey
Unsettling, intelligent, and way-out-there.
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Rolling Stone

By Peter Travers
Played as a child by Abigail Chu and as an adult by Delphine Chanéac, Dren morphs into a special-effects miracle, sexy and scary in equal doses.
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Boston Globe

By Wesley Morris
The movie begins to run out of gas as it racks up a body count, but even the mad-scientist and I-created-a-monster clichés are contorted satisfyingly enough.
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The Hollywood Reporter

Writer/director Vincenzo Natali takes his tale in some truly icky directions, not quite making it into Cronenbergland but going far enough to elicit solid 'ewww' laughs from the crowd.
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San Francisco Chronicle

By Mick LaSalle
For all its surface seriousness, Splice is a regulation monster movie. So however somber it gets, it's never truly thought-provoking, and however outrageous it gets, it's still always 20 minutes behind the audience. It's just too dumb to be serious and too slow to be entertaining. Read more: http://www.sfgate.com/cgi-bin/article.cgi?f=/c/a/2010/06/03/MVKJ1DOO26.DTL#ixzz0pqYvhKuF
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USA Today

By Claudia Puig
It's good to see Polley back on screen, after her successful turn behind the camera directing 2006's "Away From Her." She brings a measure of intelligence to the one-dimensional role.
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New York Daily News

By Joe Neumaier
Splice is an unholy mess because it fuses together the worst parts of every bad medical-monster thriller, and then boldly cranks up the ridiculous.
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66 out of 100
Generally favorable reviews
Metascore® based on all critic reviews. Scores range from 0 to 100, with higher scores indicating more favorable reviews.