- Release Date: July 30, 2010
- Run Time: 1 hr 22 min
- Rating: PG - animal action and humor
- Cast: Alec Baldwin, Chris O'Donnell, Michael Clarke Duncan
- Director: Brad Peyton
- Genre: Comedy
Synopsis: The epic struggle for control of planet Earth continues in this sequel to the 2001 comedy that had pet owners all across the world looking at their house pets in a whole new light. Chris O'Donnell and 30 Rock's Jack McBrayer head up the cast of the production, with scripting duties being handled by Brother Bear's Ron J. Friedman and Steve Bencich.