88 ReelViews | James Berardinelli The result, bolstered by strong acting and an intriguing back story, is an unqualified success. Love and Other Drugs may be the most honest romance to grace the screens during all of 2010. Read full review
75 San Francisco Chronicle | Mick LaSalle As is appropriate in a well-crafted and meticulous movie, the acting is strong down the line. Read full review
70 The Hollywood Reporter | Kirk Honeycutt In the end, this is a smart movie that could have been smarter. The script feels like it was a draft or so away from total clarity and focus. But the energy of the cast and a dive into an unfamiliar world make the movie rather addictive. Read full review
65 Movieline | Stephanie Zacharek As potentially appealing as these two actors might be, there's just nowhere for this story to go. Read full review