Ironside (Raymond Burr) investigates the mysterious disappearance of Michael Brandon (Ted Hartley), a brilliant scientist who was working on a top-secret missile project at the Gregory Institute. There are those who are convinced that Brandon has defected to the Soviets or Red Chinese, but his wife Ellie (Hildy Brooks) is adamant in her belief that her husband had met with foul play. Should Ironside trust Mrs. Brandon or the evidence of own eyes--and can there be someone else at Gregory Institute involved in the mystery? ~ Hal Erickson, Rovi