| Independent Spirit Awards |
Two Lovers |
Best Female Lead |
2009 |
Nominated |
| Hollywood Foreign Press Association |
Proof |
Best Performance by an Actress in a Motion Picture - Drama |
2005 |
Nominated |
| Toronto Film Critics Association |
The Royal Tenenbaums |
Best Supporting Actress [Runner-up] |
2001 |
Won |
| Hollywood Foreign Press Association |
Shakespeare in Love |
Best Performance by an Actress in a Motion Picture - Musical or Comedy |
1998 |
Won |
| Academy of Motion Picture Arts and Sciences |
Shakespeare in Love |
Best Actress |
1998 |
Won |
| Screen Actors Guild |
Shakespeare in Love |
Best Actress |
1998 |
Won |
| Toronto Film Critics Association |
Shakespeare in Love |
Best Actress - Runner-up |
1998 |
Won |
| National Society of Film Critics |
Flesh and Bone |
Best Supporting Actress (Runner-up) |
1993 |
Won |