Niles' fractious lady friend Dr. Mel Karnofsky (Jane Adams) has no qualms about exploiting the long-standing rivalry between Niles (David Hyde Pierce) and Frasier (Kelsey Grammer). In fact, it was Mel's idea to pit brother against brother in a wine-tasting competition -- proof positive that it is high time Niles be told that Mel is definitely not the woman for him. As for the Crane boys' dad, Martin (John Mahoney), he is having trouble making peace with himself after sleeping with the widow (Anita Gillette) of one of his oldest friends. ~ Hal Erickson, Rovi