Edmund Lowe plays a writer whose efforts to seek out story material leads him into an exhilarating adventure. Lowe gets mixed up in a murder case in which the father (Alec B. Francis) of his sweetheart (Barbara Bedford) is the principal suspect. The writer not only clears the old man but also exposes a master criminal with a dual identity. Champion of Lost Causes was based on a story by Destry and Dr. Kildare creator Max Brand. It was adapted for the screen by Thomas Dixon Jr., son of the man who wrote The Birth of a Nation (1915). ~ Hal Erickson, Rovi