Unrelated to Monogram's series of "Bowery Boys" B pictures, Republic's Bowery Boy stars Dennis O'Keefe as a crusading slum doctor. Actually, O'Keefe doesn't play the title character: that honor goes to Jimmy Lydon, a tough street kid who tries to block the plans made by O'Keefe and nurse Louise Campbell to build a health clinic. But when mobster Roger Pryor sells tainted meat that results in an outbreak of botulism, Lydon becomes O'Keefe's biggest booster. Also in the cast is Jimmy Lydon's younger brother Ormund, who plays...Jimmy Lydon's younger brother. Bowery Boy served as the directorial debut of former film editor William Morgan. ~ Hal Erickson, Rovi